Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Infectious Complications of Antibody-Drug Conjugates: A Review of Safety Data from FDA-Approved Agents.

Current oncology reports·2026

Same authorSame journal

Neoadjuvant and adjuvant therapy in uveal melanoma: toward systemic control of a systemic disease.

Cancer treatment reviews·2026

Same author

Evidence for a Potential Context-Dependent Dual Role of Eb Peptide of IGF-1Eb in Cancer Cell Survival and Adaptation to UV Stress.

International journal of molecular sciences·2026

Same author

Editorial: Current insights in melanoma immunology, immune escape and immunotherapy advances.

Frontiers in immunology·2026

Same author

Overlapping Toxicities of Pembrolizumab and Lenvatinib: A Case of Capillary Leak Syndrome with Severe Erythroblastosis.

Current oncology (Toronto, Ont.)·2026

Same author

Indirect Comparison of the Efficacy of Pembrolizumab Versus Nivolumab as Adjuvant Options for Stage IIB/IIC Melanoma.

Targeted oncology·2026

Search research articles

Related Experiment Video

Updated: Jun 6, 2026

Detection and Isolation of Circulating Melanoma Cells using Photoacoustic Flowmetry

Detection and Isolation of Circulating Melanoma Cells using Photoacoustic Flowmetry

Published on: November 25, 2011

Methods of detection of circulating melanoma cells: a comparative overview.

Andrianos Nezos¹, Pavlos Msaouel, Nikolaos Pissimissis

¹Department of Experimental Physiology, Medical School, National and Kapodistrian University of Athens, 75 Micras Asias str., Goudi-Athens 115 27, Greece. anezos@med.uoa.gr

Cancer Treatment Reviews

|November 26, 2010

Summary

Detecting circulating melanoma cells in blood is key for managing melanoma metastasis. Molecular methods aid in early detection and risk stratification for better patient outcomes.

More Related Videos

A 3D Organotypic Melanoma Spheroid Skin Model

A 3D Organotypic Melanoma Spheroid Skin Model

Published on: May 18, 2018

A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis

A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis

Published on: March 8, 2022

Related Experiment Videos

Last Updated: Jun 6, 2026

Detection and Isolation of Circulating Melanoma Cells using Photoacoustic Flowmetry

Detection and Isolation of Circulating Melanoma Cells using Photoacoustic Flowmetry

Published on: November 25, 2011

A 3D Organotypic Melanoma Spheroid Skin Model

A 3D Organotypic Melanoma Spheroid Skin Model

Published on: May 18, 2018

A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis

A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis

Published on: March 8, 2022

Area of Science:

Oncology
Molecular Biology
Cancer Metastasis Research

Background:

Melanoma dissemination significantly contributes to cancer-related mortality.
Intravascular invasion and circulation of melanoma cells lead to undetectable micrometastases, eventually progressing to overt metastasis.

Purpose of the Study:

To review current techniques for detecting, isolating, and characterizing circulating melanoma cells (CMCs) in melanoma patients.
To explore the utility of CMCs in risk stratification and clinical management.
To provide an overview of molecular markers for melanoma progression.

Main Methods:

Review of existing literature on molecular methods for CMC detection.
Analysis of techniques for isolation, enrichment, and characterization of CMCs.
Compilation of data on prognostic molecular markers in melanoma.

Main Results:

Various molecular techniques are available for CMC detection and analysis.
Early detection of CMCs can inform risk stratification.
Several molecular markers show potential as prognostic indicators for melanoma progression.

Conclusions:

Molecular detection of circulating melanoma cells is valuable for risk stratification and clinical management.
Further research into CMC detection and prognostic markers can improve melanoma patient outcomes.