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Related Experiment Video

Updated: Jun 6, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Conjunctival lymphoma in a child.

Michael Waisbourd¹, Igal Leibovitch, Dror Sayar

¹Department of Ophthalmology, Tel Aviv Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. mwaisbourd@hotmail.com

|November 26, 2010

Summary

This case report details a rare instance of large conjunctival B-cell lymphoma in a pediatric patient. Early recognition of unusual eyelid masses is crucial for timely diagnosis and treatment.

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Cell-Free DNA Extraction of Vitreous and Aqueous Humor Specimens for Diagnosis and Monitoring of Vitreoretinal Lymphoma

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Published on: January 12, 2024

Area of Science:

Ophthalmology
Pediatric Oncology
Hematology

Background:

Conjunctival lymphoma is exceedingly rare in pediatric populations.
Eyelid and conjunctival masses in children often present diagnostic challenges.

Observation:

A 13-year-old girl presented with a rapidly growing right lower eyelid mass initially misdiagnosed as a chalazion.
The mass's atypical presentation prompted an excisional biopsy for definitive diagnosis.

Findings:

Pathological examination confirmed a large B-cell lymphoma.
Immunohistochemistry revealed positive CD20 and Ki67 staining.
Polymerase chain reaction analysis demonstrated B-cell monoclonality.

Implications:

Conjunctival lymphoma should be considered in the differential diagnosis of pediatric eyelid and conjunctival masses.
Prompt biopsy is essential for accurate diagnosis of rare pediatric ocular tumors.