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[Cerebral venous thromboses in the paediatric age: clinical presentation, risk factors, diagnosis and treatment]

M Eugenia Russi1, Verónica González, Jaume Campistol

  • 1Servicio de Neuropediatría, Hospital Sant Joan de Déu, Esplugues de Llobregat, Barcelona, España. mrussi@hsjdbcn.es

Revista De Neurologia
|November 26, 2010
PubMed

Insights

Cerebral venous thrombosis is an underdiagnosed cause of childhood stroke. Early diagnosis and treatment are crucial, as this study found no complications or recurrent events in treated pediatric patients.

Area of Science:

  • Pediatric Neurology
  • Vascular Neurology
  • Pediatric Stroke

Context:

  • Cerebral venous thrombosis (CVT) is a recognized cause of ischemic stroke in children, though often underdiagnosed.
  • Understanding CVT's clinical spectrum, risk factors, and outcomes is vital for effective management.

Purpose:

  • To describe the clinical presentation, risk factors, treatment, and evolution of pediatric cerebral venous thrombosis.
  • To analyze a cohort of children diagnosed with sinovenous thrombosis.

Summary:

  • A retrospective review identified 31 pediatric cases of cerebral sinus thrombosis (2004-2009).
  • Infections were the most common risk factor (23 patients), followed by obstetric trauma (3) and prothrombotic states (5).
  • Seizures and high intracranial pressure were primary clinical presentations; anticoagulation was administered to 21 patients with no reported complications or recurrent events.

Impact:

  • Highlights the importance of considering CVT in children presenting with stroke symptoms, seizures, or intracranial hypertension.
  • Demonstrates that anticoagulation therapy for pediatric CVT is safe and effective, with no long-term adverse events observed in this cohort.
  • Emphasizes the need for increased clinical awareness and timely diagnosis of this potentially serious condition in pediatric populations.
Abstract

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