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Depression: Overview

Depression: Overview

Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...

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Treatment Strategies for Psychological Disorders

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Long-term Depression

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Long-term Depression

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Cognitive Therapy

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Depressive Disorders: MDD and Dysthymia

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Related Experiment Video

Updated: Jun 6, 2026

Animal Models of Depression - Chronic Despair Model (CDM)

Animal Models of Depression - Chronic Despair Model (CDM)

Published on: September 23, 2021

[Combatting depression using the collaborative care model].

Moniek C Vlasveld¹, Harm W J van Marwijk, Christina M van der Feltz-Cornelis

¹Trimbos-instituut, Utrecht, Afd. Diagnostiek en Behandeling, the Netherlands. mvlasveld@trimbos.nl

Nederlands Tijdschrift Voor Geneeskunde

|November 27, 2010

Summary

The collaborative care model offers a structured approach for managing depression, enhancing patient self-management and continuous symptom monitoring. This integrated care model supports general practitioners and improves access to specialist psychiatric care.

Related Experiment Videos

Last Updated: Jun 6, 2026

Animal Models of Depression - Chronic Despair Model (CDM)

Animal Models of Depression - Chronic Despair Model (CDM)

Published on: September 23, 2021

Area of Science:

Psychiatry and Mental Health
Primary Care Medicine
Health Services Research

Context:

Depression is a prevalent chronic condition requiring integrated care models beyond acute treatment approaches.
The chronic care model emphasizes patient self-management and continuous symptom monitoring for long-term conditions.
Existing primary care for depression may benefit from enhanced support and structured interventions.

Purpose:

To evaluate the collaborative care model as a promising treatment strategy for depression within primary care settings.
To highlight the benefits of integrating a care manager to support general practitioners and facilitate access to psychiatric consultation.
To assess the potential of the collaborative care model to improve depression management in the Dutch healthcare system.

Summary:

The collaborative care model integrates a care manager to support general practitioners (GPs) in managing depression.
This model facilitates structured symptom monitoring and provides easier access to consultant psychiatrists.
It aims to enhance primary care treatment for depression and strengthen collaboration between primary and specialized mental health care.

Impact:

The collaborative care model can significantly improve the management of chronic depression by enhancing primary care services.
It offers a structured framework for continuous patient monitoring and timely specialist input.
This model has the potential to optimize the interface between primary care and specialized mental health services, improving patient outcomes.