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Updated: Jun 6, 2026
14:14
Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
Published on: December 11, 2017
[Survival and disorders after percutaneous aortic valve replacement]
Amber M Otten1, Rutger J Nuis, Ron T van Domburg
1Erasmus Medisch Centrum Rotterdam, Afd. Cardiologie, Thoraxcentrum, Rotterdam, the Netherlands.
Nederlands Tijdschrift Voor Geneeskunde
|November 27, 2010
Summary
Percutaneous aortic valve replacement (PAVR) offers improved health status for high-risk patients with aortic valve stenosis but carries significant risks of mortality and stroke. PAVR should be reserved for patients unsuitable for surgical valve replacement.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Surgery
Context:
- Aortic valve stenosis (AS) is a significant cause of morbidity and mortality.
- High-risk surgical candidates require alternative treatment options.
- Percutaneous aortic valve replacement (PAVR) has emerged as a less invasive option.
Purpose:
- To describe patient characteristics undergoing PAVR for severe AS and high surgical risk.
- To evaluate the effectiveness of PAVR on survival and complications.
- To assess the impact of PAVR on patient functional status.
Summary:
- This prospective observational study analyzed 166 patients referred for PAVR, with 91 undergoing the procedure.
- PAVR patients had a mean EuroSCORE of 17%, with 30-day mortality and stroke rates of 12% and 13%, respectively.
- One-year survival was 73%, with a significant improvement in New York Heart Association (NYHA) functional class from 15% to 72%.
Impact:
- PAVR is associated with substantial risks but offers significant functional improvement in high-risk AS patients.
- The findings suggest PAVR should be primarily considered for patients unsuitable for surgical valve replacement.
- Further randomized trials are needed to definitively establish PAVR's role in AS management.
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