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Related Experiment Video

Updated: May 4, 2026

Using Eggs from Schistosoma mansoni as an In vivo Model of Helminth-induced Lung Inflammation

Using Eggs from Schistosoma mansoni as an In vivo Model of Helminth-induced Lung Inflammation

Published on: June 5, 2012

Schistosomal colonic disease.

A R Mohamed¹, M al Karawi, M I Yasawy

¹Gastroenterology Division, Armed Forces Hospital, Riyadh, Kingdom of Saudi Arabia.

|April 1, 1990

Summary

This summary is machine-generated.

Colonoscopic biopsies effectively diagnose colonic schistosomiasis, revealing Schistosoma mansoni ova in mucosa. Endoscopic findings correlate with histology, aiding in diagnosis and monitoring treatment response.

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Area of Science:

Gastroenterology
Infectious Diseases
Parasitology

Background:

Schistosomiasis is a parasitic disease affecting various organs, including the colon.
Accurate diagnosis of colonic schistosomiasis is crucial for effective management.

Purpose of the Study:

To evaluate the diagnostic utility of colonoscopy and endoscopic biopsies in patients with suspected colonic schistosomiasis.
To correlate endoscopic findings with histopathological results and clinical symptoms.

Main Methods:

Retrospective analysis of 216 patients diagnosed with colonic schistosomiasis via endoscopic biopsies.
Colonoscopy, stool examination for Schistosoma mansoni ova, and histopathological analysis of colonic biopsies were performed.

Main Results:

Colonoscopy suggested schistosomiasis in 45.37% of patients; stool ova were found in only 11.11%.
Histopathology revealed Schistosoma mansoni ova in colonic mucosa as the most common finding, correlating with endoscopic appearance.
Abdominal pain/distention were common symptoms; hepatosplenic involvement occurred in 30.09%.

Conclusions:

Colonoscopy is valuable for identifying characteristic colonic lesions in schistosomiasis.
Endoscopic biopsies are diagnostic for colonic schistosomiasis and correlate with histological findings.
Treatment led to normalization of endoscopic findings in some patients.