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Prevalence of cryptosporidium species in paediatric patients in Eastern Nepal

Ritu Amatya1, Nimesh Poudyal, Rajendra Gurung

  • 1Department of Microbiology, BP Koirala Institute of Health Sciences, Dharan, Koshi, Nepal.

Tropical Doctor
|November 27, 2010
PubMed

Insights

Cryptosporidium is a common cause of childhood diarrhea in Nepal. This study found Cryptosporidium in 4.1% of diarrheal cases among children, with higher prevalence during the rainy season.

Area of Science:

  • Medical Parasitology
  • Pediatric Gastroenterology
  • Infectious Diseases

Background:

  • Cryptosporidium species are significant pathogens causing childhood diarrhea globally.
  • Understanding the prevalence of cryptosporidiosis in specific regions is crucial for public health interventions.

Purpose of the Study:

  • To determine the prevalence of cryptosporidiosis in HIV-seronegative children presenting with diarrhea in Nepal.
  • To identify the occurrence of other intestinal parasites in the same cohort.

Main Methods:

  • Stool samples were collected from children aged 15 years and below over a 12-month period.
  • Modified acid-fast staining was employed for the detection of coccidian oocysts.
  • Analysis included identification of all intestinal parasites present.

Main Results:

  • Intestinal parasites were detected in 9.15% of diarrheal stool samples.
  • Coccidian parasites, including Cryptosporidium (4.1%) and Cyclospora (0.3%), were found in 4.4% of samples.
  • Coccidia were the most frequently identified parasites, with year-round detection peaking during the rainy season.

Conclusions:

  • Cryptosporidium is a notable cause of diarrhea in young children in this region of Nepal.
  • The findings highlight the importance of parasitic infections, particularly coccidia, in pediatric diarrheal diseases.
  • Seasonal patterns suggest potential environmental or transmission factors influencing cryptosporidiosis outbreaks.

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