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Related Concept Videos

Reticular Dermis01:15

Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
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The seminal work of Ohno in 1970 popularized the idea of gene duplication and divergence. DNA sequence comparison studies reveal that a large portion of the genes in bacteria, archaebacteria, and eukaryotes was  generated by gene duplication and divergence, indicating its critical role in evolution.
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Related Experiment Video

Updated: Jun 6, 2026

Preparation of Adult Drosophila Eyes for Thin Sectioning and Microscopic Analysis
07:49

Preparation of Adult Drosophila Eyes for Thin Sectioning and Microscopic Analysis

Published on: August 27, 2011

Evolution of reticular pseudodrusen.

John Sarks1, Jennifer Arnold, I-Van Ho

  • 1Department of Ophthalmology, Prince of Wales Hospital, Randwick, Sydney, Australia. jssarks@bigpond.net.au

The British Journal of Ophthalmology
|November 27, 2010
PubMed
Summary
This summary is machine-generated.

Reticular pseudodrusen (RPD) may be transient and potentially linked to subretinal material, often associated with age-related macular degeneration (AMD). Their prevalence might be underestimated due to imaging and examination factors.

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Area of Science:

  • Ophthalmology
  • Retinal Imaging
  • Pathology

Background:

  • Reticular pseudodrusen (RPD) are recognized as a potential risk factor for developing age-related macular degeneration (AMD).
  • Clinical recognition of RPD can be challenging due to variations in appearance and imaging techniques.
  • Understanding the underlying pathology of RPD is crucial for accurate diagnosis and prognosis.

Purpose of the Study:

  • To describe the clinical characteristics and evolution of reticular pseudodrusen (RPD).
  • To investigate the potential pathological basis of RPD.
  • To assess the association of RPD with age-related macular degeneration (AMD) and choroidal neovascularization (CNV).

Main Methods:

  • Retrospective analysis of 166 patients with RPD and over 1 year of follow-up.
  • Utilized multiple imaging techniques to observe RPD evolution.
  • Recorded associated macular changes and AMD manifestations.

Main Results:

  • RPD initially appeared as a reticular network, later becoming diffuse and yellowish.
  • RPD faded around choroidal neovascularization (CNV) and could be transient.
  • High association with AMD (nearly all eyes) and CNV (52.1%) was observed.
  • Clinicopathological examination revealed abnormal material in the subretinal space in one case.

Conclusions:

  • The prevalence of RPD may be underestimated due to dependence on imaging methods and examination area.
  • RPD might represent material located in the subretinal space.
  • Clinical recognition requires careful consideration of imaging and potential confusion with typical drusen.