Related Experiment Video
Updated: Jun 6, 2026

Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation
Published on: October 15, 2021
Emergency management of minor head injury in anticoagulated patients
1School of Health and Related Research, Regent Court, 30 Regent Street, Sheffield S1 4DA, UK. aleiblich@doctors.org.uk
Approximately 1% of the UK population receives anticoagulation with warfarin. Head injury accounts for some 1.4 million emergency department attendances in the country. Therefore, significant numbers of patients with head injury have a therapeutic coagulopathy. This review aims to examine the existing evidence for optimal management of warfarinised head injured patients, particularly with respect to the need for early CT imaging and the use of reversal agents in cases of proved haemorrhage.
Approximately 1% of the UK population receives anticoagulation with warfarin. Head injury accounts for some 1.4 million emergency department attendances in the country. Therefore, significant numbers of patients with head injury have a therapeutic coagulopathy. This review aims to examine the existing evidence for optimal management of warfarinised head injured patients, particularly with respect to the need for early CT imaging and the use of reversal agents in cases of proved haemorrhage.
Related Concept Videos
Venous Thrombosis IV: Nursing Management
Anticoagulant Drugs: Low-Molecular-Weight Heparins
Venous Thrombosis III: Interprofessional Care
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Acute Coronary Syndrome IV: Interprofessional Care
Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...

