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Duodenojejunal intussusception in Peutz-Jeghers syndrome: Report of a case

Senthil Kumar Aiyappan1, Mandeep Kang, Thakur Deen Yadav

  • 1Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Sector-12, Chandigarh, 160012, India.

Surgery Today
|November 27, 2010
PubMed

Insights

Recurrent intussusception is common in Peutz-Jeghers syndrome. This case highlights synchronous duodenojejunal and jejunojejunal intussusceptions caused by hamartomatous polyps, a rare presentation.

Area of Science:

  • Gastroenterology
  • Medical Genetics
  • Surgical Pathology

Background:

  • Peutz-Jeghers syndrome is an inherited disorder characterized by hamartomatous polyps in the gastrointestinal tract.
  • Intussusception, particularly recurrent intussusception, is a known complication associated with Peutz-Jeghers syndrome.
  • Hamartomatous polyps serve as a lead point for intussusception by invaginating into the bowel lumen.

Observation:

  • This report details a rare case of Peutz-Jeghers syndrome presenting with synchronous duodenojejunal and jejunojejunal intussusceptions.
  • The intussusceptions were directly attributed to the presence of hamartomatous polyps acting as lead points.
  • Duodenojejunal intussusception, specifically, is infrequently documented in the context of Peutz-Jeghers syndrome.

Findings:

  • The study confirms hamartomatous polyps as the etiology for both duodenojejunal and jejunojejunal intussusceptions in this Peutz-Jeghers syndrome patient.
  • Synchronous occurrence of these two distinct intussusception types represents a unique clinical scenario.
  • The findings underscore the potential for complex intussusception patterns in Peutz-Jeghers syndrome.

Implications:

  • This case expands the understanding of intussusception presentations in Peutz-Jeghers syndrome, particularly the rarer duodenojejunal variant.
  • It highlights the importance of considering Peutz-Jeghers syndrome in patients with unexplained or recurrent intussusceptions, even with unusual locations.
  • Early recognition and management are crucial to prevent complications such as bowel obstruction or ischemia in patients with Peutz-Jeghers syndrome and intussusception.

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