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Gender differences in survival following hospitalisation for COPD
Anne V Gonzalez1, Samy Suissa, Pierre Ernst
1Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, McGill University Health Centre, Montreal, Canada. anne.gonzalez@mcgill.ca
Thorax
|November 30, 2010
Summary
Men with chronic obstructive pulmonary disease (COPD) face higher mortality and rehospitalisation risks compared to women. This large cohort study highlights significant gender-based outcome differences in elderly COPD patients.
Area of Science:
- Pulmonary Medicine
- Epidemiology
- Geriatrics
Background:
- Chronic obstructive pulmonary disease (COPD) is a major global health concern.
- While gender differences in COPD presentation are known, outcome disparities require systematic investigation.
- This study examines gender-specific survival and rehospitalisation rates in elderly COPD patients.
Purpose of the Study:
- To investigate gender differences in survival and rehospitalisation rates among elderly patients hospitalised for COPD.
- To determine the impact of male gender on all-cause mortality and rehospitalisation risk in this population.
Main Methods:
- Utilised Québec health insurance plan databases for a large cohort aged over 66 years (1990-2001).
- Included patients with a first COPD hospitalisation, followed until 2003.
- Employed Kaplan-Meier and Cox proportional hazards models to analyse mortality and rehospitalisation risks associated with male gender.
Main Results:
- The cohort comprised 19,260 women and 23,893 men (mean age 77).
- Men exhibited significantly higher all-cause mortality (adjusted HR 1.45) and rehospitalisation risk (adjusted HR 1.12) for obstructive airways disease.
- 58.4% of women and 70.1% of men died during follow-up.
Conclusions:
- Female patients with COPD demonstrate significantly better mean survival rates.
- Women also experience a longer time to rehospitalisation for obstructive airways disease compared to men.
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