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Related Concept Videos

Cancer Cell Migration through Invadopodia01:35

Cancer Cell Migration through Invadopodia

Invadosome is a broad category of cell surface structures with proteolytic activity that  degrades the extracellular matrix (ECM). Invadosomes are present in normal cell types, including macrophages, endothelial cells, and neurons, as well as tumor cells. Although the macrophage podosomes and tumor cell invadopodia are classified as invadosomes, they have different structures, molecular pathways, and functions. Podosomes are short structures that last for a few minutes. However, invadopodia can...

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Invasive Papillary Breast Carcinoma.

S J Bhosale1, A Y Kshirsagar, S R Sulhyan

  • 1Krishna Institute of Medical Sciences University, Karad, India.

Case Reports in Oncology
|November 30, 2010
PubMed
Summary

A 55-year-old woman successfully treated for invasive papillary carcinoma, a type of breast cancer, shows no signs of recurrence after surgery and chemotherapy. This case highlights effective management of early-stage breast cancer.

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Area of Science:

  • Oncology
  • Pathology

Background:

  • Invasive papillary carcinoma is a rare subtype of breast cancer.
  • Early detection and prompt treatment are crucial for favorable outcomes.

Observation:

  • A 55-year-old postmenopausal female presented with a painless, gradually increasing subareolar breast mass.
  • The mass was present for 4 months.

Findings:

  • Histopathological diagnosis confirmed invasive papillary carcinoma.
  • Immunohistochemistry supported the diagnosis.
  • Modified radical mastectomy revealed no malignant cells in 8 excised axillary lymph nodes.
  • The patient completed postoperative chemotherapy.

Implications:

  • This case demonstrates a successful treatment outcome for invasive papillary carcinoma.
  • The patient remains recurrence-free at 6-month follow-up.
  • Effective management strategies contribute to positive prognoses in early-stage breast cancer.