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Related Experiment Video

Updated: Jun 6, 2026

Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma
04:01

Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma

Published on: September 15, 2023

Thyroidectomy and lymph node dissection in papillary thyroid carcinoma.

Yasuhiro Ito1, Akira Miyauchi

  • 1Departments of Surgery, Kuma Hospital, 8-2-35, Shimoyamate-dori, Chuo-ku, Kobe City 650-0011, Japan.

Journal of Thyroid Research
|November 30, 2010
PubMed
Summary
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Serum Thyroid Hormone Balance in Levothyroxine Monotherapy-Treated Patients with Atrophic Thyroid After Radioiodine Treatment for Graves' Disease.

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CD44v8-10 and CD44s Are Age-dependently Expressed in Primary Cultured Papillary Thyroid Carcinoma Cells and Are Associated with Cell Proliferation.

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Control of Lung Metastases and Colon Polyposis with Lenvatinib Therapy in a Patient with Cribriform-Morular Variant of Papillary Thyroid Carcinoma and an <i>APC</i> Gene Mutation: A Case Study.

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Acoustic Breathiness Index for the Japanese-Speaking Population: Validation Study and Exploration of Affecting Factors.

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<i>TERT</i> mRNA Expression as a Novel Prognostic Marker in Papillary Thyroid Carcinomas.

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Papillary thyroid carcinoma treatment varies globally. This study advocates for personalized surgical strategies based on clinicopathological features, moving beyond standardized approaches for better patient outcomes.

Area of Science:

  • Endocrinology
  • Oncology
  • Surgical Pathology

Background:

  • Papillary carcinoma, a follicular cell malignancy, is typically indolent but can present with poor prognosis based on specific features.
  • Current treatment paradigms differ significantly between Western countries (total thyroidectomy with radioactive iodine ablation) and Japan (limited thyroidectomy with prophylactic lymph node dissection).

Purpose of the Study:

  • To discuss appropriate surgical management for papillary thyroid carcinoma.
  • To emphasize personalized treatment based on clinicopathological features, informed by international guidelines and clinical experience.

Main Methods:

  • Review of Western and Japanese guidelines for papillary thyroid carcinoma treatment.
  • Analysis of preoperative imaging, particularly ultrasonography, for accurate staging.

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  • Consideration of clinical experience from Kuma Hospital.
  • Main Results:

    • Preoperative imaging, especially ultrasonography, allows for accurate cancer staging.
    • Stereotyped treatment approaches may not be optimal for all papillary carcinoma patients.

    Conclusions:

    • Tailoring thyroidectomy extent and lymph node dissection to individual clinicopathological features is crucial.
    • Personalized treatment strategies are recommended for papillary thyroid carcinoma management.