Electrochemiluminescence induced photoelectrochemistry for sensing of the DNA based on DNA-linked CdS NPs

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Published on: June 1, 2011

Yingshu Guo1, Yuanshun Sun, Shusheng Zhang

  • 1State Key Laboratory Base of Eco-chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, China.

Chemical Communications (Cambridge, England)
|November 30, 2010
PubMed

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Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...