Related Experiment Video
Updated: Jun 6, 2026

Single-cell Analysis of Immunophenotype and Cytokine Production in Peripheral Whole Blood via Mass Cytometry
Published on: June 26, 2018
Clinical and laboratory characteristics of patients with sickle-cell and autoimmune/connective tissue diseases
Salam Alkindi1, Mustafa Al-Maini, Anil Pathare
1Department of Haematology, Sultan Qaboos University, P.O. Box 35, Muscat 123, Sultanate of Oman. sskindi@yahoo.com
Abstract:
Patients with sickle-cell disease who develop autoimmune connective tissue disorders can present with similar clinical manifestations and/or complications making them indistinguishable. We report here a single-institution study on a cohort of 24 patients, with the above combination. The results suggest that there is often a significant delay in making the second diagnosis because of the overlapping clinical profile. It is emphasized that the clinician should be aware of and vigilant about such cases and should diligently follow up such cases to make an early diagnosis and start the appropriate treatment.
Related Concept Videos
Chronic Kidney Disease II: Clinical Manifestations
Autoimmune Disorders
Concept and Mechanism of Autoimmune Diseases
The immune system...
Connective Tissue Cell Types
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...
Multiple Allele Traits
Introduction to Connective Tissues
Endocarditis II: Clinical Features of Infective Endocarditis
