Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ultrasound II: Endoscopic Ultrasound and FibroScan01:25

Ultrasound II: Endoscopic Ultrasound and FibroScan

Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
Endoscopic Ultrasound (EUS):
Hepatitis01:25

Hepatitis

Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver. The...
Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test01:22

Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test

In clinical practice, the direct measurement of hepatic blood flow to evaluate liver function presents significant challenges due to the intricate and specialized nature of the necessary techniques. Consequently, healthcare professionals often rely on empirical estimates derived from thorough patient examinations and liver function tests to gauge liver health. Among the tools at their disposal, the Child–Pugh and MELD scoring systems stand out for their ability to categorize and assess the...
Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Equity in medical school interviews: a cross-sectional analysis of school type, gender, and widening participation status.

BMC medical education·2026
Same author

Generative artificial intelligence adoption and use in teaching and training healthcare professionals in higher education in the United States: a cross-sectional study.

BMC medical education·2026
Same author

Healthcare Providers' Perspectives on Generative Artificial Intelligence (GenAI) Adoption, Adaptation, Assimilation, and Use in the United States.

Healthcare (Basel, Switzerland)·2026
Same author

Transforming Public Health Practice with Artificial Intelligence: A Framework-Driven Approach.

Healthcare (Basel, Switzerland)·2026
Same author

Uncovering the genetic landscape of cholangiocarcinoma and its subtypes via GWAS and integrative analyses.

Hepatology (Baltimore, Md.)·2026
Same author

Cholangiocarcinoma 2026: status quo, unmet needs and priorities.

Nature reviews. Gastroenterology & hepatology·2025

Related Experiment Video

Updated: Jun 6, 2026

A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
12:24

A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma

Published on: September 30, 2021

Hepatocellular carcinoma: diagnostics and screening.

Madhvi Patel1, Mohamed I F Shariff, Nimzing G Ladep

  • 1Division of Diabetes Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, UK.

Journal of Evaluation in Clinical Practice
|December 1, 2010
PubMed
Summary

Hepatocellular carcinoma (HCC), a major liver cancer, is rising globally. Early detection through advanced screening methods is crucial for improving survival rates in patients with liver cirrhosis.

More Related Videos

An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis
06:38

An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis

Published on: September 12, 2019

Non-Invasive PET/MR Imaging in an Orthotopic Mouse Model of Hepatocellular Carcinoma
07:47

Non-Invasive PET/MR Imaging in an Orthotopic Mouse Model of Hepatocellular Carcinoma

Published on: August 31, 2022

Related Experiment Videos

Last Updated: Jun 6, 2026

A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
12:24

A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma

Published on: September 30, 2021

An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis
06:38

An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis

Published on: September 12, 2019

Non-Invasive PET/MR Imaging in an Orthotopic Mouse Model of Hepatocellular Carcinoma
07:47

Non-Invasive PET/MR Imaging in an Orthotopic Mouse Model of Hepatocellular Carcinoma

Published on: August 31, 2022

Area of Science:

  • Hepatology
  • Oncology
  • Epidemiology

Background:

  • Hepatocellular carcinoma (HCC) is a prevalent primary liver cancer and a leading cause of cancer mortality worldwide.
  • Its incidence is increasing globally, particularly in developed nations, often associated with cirrhosis.
  • Chronic hepatitis B and C infections are primary risk factors for HCC development.

Purpose of the Study:

  • To review epidemiological trends and risk factors for HCC.
  • To discuss current diagnostic techniques and screening guidelines.
  • To explore emerging technologies for early hepatocarcinogenesis detection.

Main Methods:

  • Literature review of epidemiological data.
  • Analysis of current diagnostic and screening guidelines.
  • Examination of recent technological advancements in early cancer detection.

Main Results:

  • HCC incidence is rising, with significant global disparities.
  • Existing diagnostic tools like ultrasound and alpha-fetoprotein lack optimal sensitivity.
  • New technologies offer promise for earlier identification of hepatocarcinogenesis.

Conclusions:

  • Early diagnosis of HCC is critical for improving patient survival.
  • Current screening methods require enhancement for better tumor detection.
  • Advancements in screening technologies are vital for combating HCC.