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Diet and iron deficiency in the first year of life: a retrospective study
L Capozzi1, R Russo, F Bertocco
1Department of Pediatrics, Second University of Naples, Via de Crecchio no. 4, Naples, Italy.
Insights
Formula milk and early weaning (before 6 months) are linked to better infant iron levels and hemoglobin. Breast milk and cow's milk feeding showed lower iron stores in infants.
Area of Science:
- Pediatrics
- Nutrition Science
- Public Health
Background:
- Infant nutrition significantly impacts iron status and hemoglobin levels.
- Breast milk (BM), formula milk (FM), and cow's milk (CM) have varying effects on infant health.
- Early childhood iron deficiency remains a global health concern.
Purpose of the Study:
- To investigate the relationship between milk feeding types, weaning practices, and infant iron stores.
- To assess the influence of socioeconomic status on hemoglobin and iron levels in infants.
- To determine optimal feeding and weaning strategies for maintaining adequate iron status.
Main Methods:
- Observational cohort study of 385 infants.
- Analysis of hemoglobin (Hb) and ferritin levels at 8 and 12 months.
- Comparison of iron status based on milk feeding (BM, FM, CM), age of weaning, and socioeconomic factors.
Main Results:
- Lower hemoglobin (<11 g/dl) and iron stores (<15 ng/ml) were more frequent in BM and CM groups compared to FM (P<0.05).
- Infants fed formula milk and weaned before 6 months exhibited better Hb and ferritin levels.
- Socioeconomic status significantly influenced diet, Hb levels, and iron stores.
Conclusions:
- Formula milk feeding and early weaning (<6 months) are associated with improved infant iron status.
- Breast milk and cow's milk feeding may be linked to lower iron stores, particularly in certain socioeconomic contexts.
- Early intervention and nutritional guidance are crucial for preventing iron deficiency in infants.
Abstract:
In an observational cohort of 385 infants, we have investigated the relationship between hemoglobin (Hb) levels and iron stores and the type of milk feeding [breast milk (BM), formula milk (FM), cow's milk (CM), age and type of weaning, and socioeconomic status] at 8 and 12 months of age. Levels of Hb<11 g/dl and iron stores <15 ng/ml were significantly more frequent in BM and CM groups than in FM group (P<0·05). Significant differences of Hb mean were observed among the three groups, while ferritin mean were lower in BM and CM groups than in FM group (P<0·05). Socioeconomic factors also influenced Hb levels and iron stores through differences in diet. Deprived infants were 23·1% of cohort and many of them received BM (43·5% at 8 months versus 38·5% at 12 months) or CM (42·6% at 8 months versus 47% at 12 months), while >50% were weaned before 6th month of age. FM feeding and weaning <6 months of age are related with better Hb levels and iron stores. Analysis of the impact of weaning on Hb levels and iron stores showed that infants weaned <6 months of life had, regardless of milk feeding, higher Hb and ferritin levels than weaned >6 months.
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