Related Experiment Video
Updated: Jun 6, 2026

In Vitro Chemical Mapping of G-Quadruplex DNA Structures by Bis-3-Chloropiperidines
Published on: May 12, 2023
Molecular aspects on the interaction of quercetin and its metal complexes with DNA
Jafar Ezzati Nazhad Dolatabadi1
1Research Center for Pharmaceutical Nanotechnology, Tabriz University of Medical Sciences, Daneshgah Street, Tabriz, Iran.
Abstract:
Flavonoids occupy an important position in chemistry and pharmacology. Various flavonoids, particularly quercetin have potential to form molecular complexes with nucleic acid structure and have attracted recent attention for their prospective clinical and pharmacological utility. This review highlights the properties of quercetin and its different metal complexes as well as their interactions with DNA reported by several research groups. Various analytical techniques were employed including absorbance, fluorescence and circular dichroism spectroscopies, viscosity and voltammetry to provide more details about binding mechanism of these materials with DNA.
More Related Videos
09:00An In Vitro Enzymatic Assay to Measure Transcription Inhibition by Gallium(III) and H3 5,10,15-tris(pentafluorophenyl)corroles
Published on: March 18, 2015
11:38Quantifying the Binding Interactions Between Cu(II) and Peptide Residues in the Presence and Absence of Chromophores
Published on: April 5, 2022
Related Concept Videos
Complexation Equilibria: The Chelate Effect
EDTA: Chemistry and Properties
Metal-Ligand Bonds
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
Inhibitors of Bacterial DNA Synthesis
EDTA: Auxiliary Complexing Reagents
Complexometric Titration: Ligands