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Cell-specific expression of TLR9 isoforms in inflammation.

Kelly J McKelvey1, John Highton, Paul A Hessian

  • 1Department of Physiology, Otago School of Medical Sciences, University of Otago, PO Box 913, Dunedin 9054, New Zealand. mckke191@student.otago.ac.nz

Journal of Autoimmunity
|December 1, 2010
PubMed
Summary

Different Toll-like receptor 9 (TLR9) isoforms are expressed by immune cells, influencing inflammation. B-lymphocytes predominantly express TLR9-A, while T-lymphocytes and monocytes express TLR9-C, impacting inflammatory responses.

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