Related Experiment Video
Updated: Jun 6, 2026

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans
Published on: October 17, 2018
Maximal heart rate prediction in adults that are overweight or obese
Shawn C Franckowiak1, Devon A Dobrosielski, Suzanne M Reilley
1Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. sfrancko@jhmi.edu
Abstract:
An accurate predictor of maximal heart rate (MHR) is necessary to prescribe safe and effective exercise in those considered overweight and obese when actual measurement of MHR is unavailable or contraindicated. To date, accuracy of MHR prediction equations in individuals that are overweight or obese has not been well established. The purpose of this study was to examine the accuracy of 3 equations for predicting MHR in adults that are overweight or obese. One hundred seventy-three sedentary adults that were overweight or obese enrolled in weight-loss study and performed a VO₂peak treadmill test before the start of the weight loss treatment. A total of 132 of the 173 participants met conditions for achieving maximal exercise testing criteria and were included in this study. Maximal heart rate values determined from VO₂peak treadmill tests were compared across gender, age, and weight status with the following prediction equations: (a) 220 - age, (b) 208 - 0.7 × age, and (c) 200 - 0.48 × age. Among 20- to 40-year-old participants, actual MHR averaged 180 ± 9 b·min⁻¹ and was overestimated (p < 0.001) at 186 ± 5 b·min⁻¹ with the 220 - age equation. Weight status did not affect predictive accuracy of any of the 3 equations. For all participants, the equation, 200-0.48 × age estimated MHR to be 178 ± 4 b·min⁻¹, which was greater than the actual value (175 ± 12, p = 0.005). Prediction equations showed close agreement to actual MHR, with 208 - 0.7 × age being the most accurate.
Related Concept Videos
Factors Influencing Heart Rate
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
Exercise and Cardiac Output
Sustained exercise increases the muscles' oxygen demand, which can be met...
Drug Dosing: Obese Patients
Obesity
Regulation of Heart Rates
The SNS increases heart rate through the release of norepinephrine and epinephrine, which act on beta-1 adrenergic receptors in the heart. This action increases the rate of depolarization in the sinoatrial (SA) node, the heart's...
Cardiac Output I:Effect of Heart Rate on Cardiac Output
Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
Effect of Heart Rate on Cardiac Output
Cardiac output adapts to metabolic demands during stress, physical activity, or illness. The autonomic nervous system regulates heart rate via the sinoatrial node. The parasympathetic nervous system decreases heart rate...

