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$Microfluidic Chips for In Situ Crystal X-ray Diffraction and In Situ Dynamic Light Scattering for Serial Crystallography$

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Non-destructive and quantitative imaging of a nano-structured microchip by ptychographic hard X-ray scanning

A Schropp¹, P Boye, A Goldschmidt

¹Institute of Structural Physics, Technische Universität Dresden, Dresden, Germany. schropp@xray-lens.de

Journal of Microscopy

|December 2, 2010

Abstract:

We used hard X-ray scanning microscopy with ptychographic coherent diffraction contrast to image a front-end processed passivated microchip fabricated in 80 nm technology. No sample preparation was needed to image buried interconnects and contact layers with a spatial resolution of slightly better than 40 nm. The phase shift in the sample is obtained quantitatively. With the additional knowledge of the elemental composition determined in parallel by X-ray fluorescence mapping, quantitative information about specific nanostructures is obtained. A significant enhancement in signal-to-noise ratio and spatial resolution is achieved compared to conventional hard X-ray scanning microscopy.

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