Related Experiment Video
Updated: Jun 6, 2026

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
Published on: May 1, 2015
Hyperplasia of lymphoid structures in the hypopharynx: a case report
Yuh Baba1, Yasumasa Kato, Kaoru Ogawa
1Department of Otorhinolaryngology, Ohtawara Red Cross Hospital, 2-7-3 Sumiyoshi-cho Ohtawara City, Tochigi 324-8686, Japan. yuh_baba@hotmail.com.
Introduction:
Ectopic tonsillar tissue simulating a benign tumor of the hypopharynx is described in this report.
Case Presentation:
We report the case of a 79-year-old Japanese woman with globus sensation. Because clinical observation revealed benign features, tumor tissue was laryngoscopically resected. From the pathological features, for example, existence of germinal center, lymphoid tissue, and crypt involving lymphoepithelial symbiosis, we diagnosed that the lesion was a hyperplasia of ectopic tonsillar tissue.
Conclusions:
Although ectopic tonsillar tissue of the hypopharynx is relatively rare, it should be kept in mind during differential diagnosis.
Related Concept Videos
Lymphoid Cells and Tissues
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
Cellular Adaptation III: Hyperplasia
Chronic Pharyngitis
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Cellular Adaptation IV: Dysplasia and Metaplasia
Secondary Lymphoid Organs
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
Primary Lymphoid Organs
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...