Related Experiment Video
Updated: Jun 6, 2026

08:49
A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Melanoma markers-negative primary melanoma with melanoma markers-positive metastasis
Anuradha Sheth1, Nebojsa Arsenovic
1Lincoln County Hospital, Lincoln, UK.
International Journal of Surgical Pathology
|December 2, 2010
Abstract:
Concordant loss of all 3 commonly used melanocytic markers (ie, S-100, HMB-45, and Melan-A) in a primary malignant melanoma with expression of the same in the metastatic lesion is very rare. To the best of the authors' knowledge, they documented the second case of this unusual and rare phenomenon.
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