Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...
Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
Cardiomyopathy I: Introduction and Classification01:25

Cardiomyopathy I: Introduction and Classification

Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multimodal phenotypic clustering predicts cardiac outcomes in Fabry disease.

Orphanet journal of rare diseases·2026
Same author

Clinical guideline for ventilation-perfusion scintigraphy in pulmonary hypertension.

Nuclear medicine communications·2025
Same author

Large Vessel Vasculitis: Multimodality Imaging Findings and Technical Principles.

Radiographics : a review publication of the Radiological Society of North America, Inc·2025
Same author

Clinically relevant outcomes for research in pediatric pulmonary embolism: communication from the ISTH SSC Subcommittee on Pediatric/Neonatal Thrombosis and Hemostasis.

Journal of thrombosis and haemostasis : JTH·2025
Same author

Challenges in achieving LDL-C goals: Insights from the Italian SANTORINI study cohort.

Nutrition, metabolism, and cardiovascular diseases : NMCD·2025
Same author

Effect of obicetrapib, a potent cholesteryl ester transfer protein inhibitor, on p-tau217 levels in patients with cardiovascular disease.

The journal of prevention of Alzheimer's disease·2025
Same journal

Prognostic value of preoperative peak atrial longitudinal strain for patients undergoing mitral valve surgery.

Journal of cardiovascular medicine (Hagerstown, Md.)·2026
Same journal

From photoshop to artificial intelligence. Scientific integrity in the modern era of cardiovascular research: a call for action.

Journal of cardiovascular medicine (Hagerstown, Md.)·2026
Same journal

When cancer meets acute coronary syndrome: moving beyond the 'cancer disadvantage'.

Journal of cardiovascular medicine (Hagerstown, Md.)·2026
Same journal

In-hospital outcomes of acute coronary syndrome in patients with cancer: a systematic review and meta-analysis.

Journal of cardiovascular medicine (Hagerstown, Md.)·2026
Same journal

Differentiating Takotsubo syndrome from anterior STEMI: are we getting closer?

Journal of cardiovascular medicine (Hagerstown, Md.)·2026
Same journal

A new milestone for the Journal of Cardiovascular Medicine.

Journal of cardiovascular medicine (Hagerstown, Md.)·2026
See all related articles

Related Experiment Video

Updated: Jun 6, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
08:13

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

Published on: February 16, 2016

Left ventricular noncompaction.

Neil Mangrolia1, Timothy Watson, Deepa Gopalan

  • 1Department of Cardiology, Addenbrooke's Hospital, Cambridge, UK.

Journal of Cardiovascular Medicine (Hagerstown, Md.)
|December 2, 2010
PubMed
Summary
This summary is machine-generated.

Left ventricular noncompaction, a rare cardiomyopathy, presents with prominent ventricular hypertrabeculation. This case highlights diagnostic imaging findings in a patient with atrial fibrillation.

More Related Videos

Induction of Right Ventricular Failure by Pulmonary Artery Constriction and Evaluation of Right Ventricular Function in Mice
09:40

Induction of Right Ventricular Failure by Pulmonary Artery Constriction and Evaluation of Right Ventricular Function in Mice

Published on: May 13, 2019

Point-of-Care Ultrasound for Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Without Left Ventricular Venting
03:40

Point-of-Care Ultrasound for Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Without Left Ventricular Venting

Published on: January 17, 2025

Related Experiment Videos

Last Updated: Jun 6, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
08:13

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

Published on: February 16, 2016

Induction of Right Ventricular Failure by Pulmonary Artery Constriction and Evaluation of Right Ventricular Function in Mice
09:40

Induction of Right Ventricular Failure by Pulmonary Artery Constriction and Evaluation of Right Ventricular Function in Mice

Published on: May 13, 2019

Point-of-Care Ultrasound for Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Without Left Ventricular Venting
03:40

Point-of-Care Ultrasound for Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Without Left Ventricular Venting

Published on: January 17, 2025

Area of Science:

  • Cardiology
  • Medical Imaging

Background:

  • Left ventricular noncompaction (LVNC) is a rare congenital cardiomyopathy.
  • It is characterized by excessive prominent trabeculations and deep recesses in the left ventricle.

Observation:

  • A 30-year-old man presented with rapidly conducted atrial fibrillation.
  • Diagnostic imaging revealed characteristic features of LVNC.

Findings:

  • Prominent ventricular hypertrabeculation was observed.
  • Echocardiography and MRI showed a noncompacted to compacted myocardial thickness ratio > 2.

Implications:

  • This case underscores the importance of recognizing LVNC in patients with arrhythmias.
  • Advanced imaging techniques are crucial for diagnosing this cardiomyopathy.