Related Experiment Video
Updated: Jun 6, 2026

Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins
Published on: July 8, 2025
Risk factors for acquisition of endemic blastomycosis
Maxym Choptiany1, Lyle Wiebe, Bill Limerick
1Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba;
Background:
Blastomycosis is potentially fatal, but environmental risk factors for acquiring blastomycosis are not well established.
Method:
Matched cross-sectional questionnaire of 112 patients with history of blastomycosis and 118 control subjects in Manitoba and northwestern Ontario.
Results:
The most common tissues involved with blastomycosis were pulmonary, skin and soft tissues, and bone. A significantly greater proportion of patients with blastomycosis than control subjects were involved in outdoor occupations. A significantly greater percentage of patients with blastomycosis were immunosuppressed either from collagen vascular disease or immunosuppressive therapy, or had hypothyroidism. A significant association between canine and human blastomycosis was not observed.
Conclusions:
Independent risk factors for development of blastomycosis included immunosuppression for any reason (including drugs or disease), collagen vascular disease, being an outdoor worker, and having a coworker with blastomycosis. Canine blastomycosis was not a risk factor for human disease in dog owners.
Related Concept Videos
Fungal Phylum Microsporidia
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Amebiasis
Cryptococcal Meningitis
Leishmaniasis
Tuberculosis
