Related Experiment Video
Updated: Jun 6, 2026

Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure
Published on: July 30, 2009
Discomfort in children undergoing unsedated MRI
Anna E Westra1, Maria P A Zegers, Rám N Sukhai
1Department of Pediatrics, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, The Netherlands. a.e.westra@lumc.nl
Insights
Pediatric Magnetic Resonance Imaging (MRI) scans cause minimal discomfort for most children. Parental anxiety and contrast dye use were linked to increased distress in children undergoing MRI.
Area of Science:
- Pediatric imaging
- Medical physics
- Child psychology
Background:
- Research Magnetic Resonance Imaging (MRI) in children requires ethical review to ensure minimal harm.
- Assessing discomfort in pediatric MRI is crucial for patient well-being and procedural consent.
Purpose of the Study:
- To provide empirical data on discomfort experienced by unsedated children (5-12 years) during MRI scans.
- To investigate the relationship between age and MRI-related discomfort in children.
- To identify subject and procedural characteristics associated with increased discomfort during pediatric MRI.
Main Methods:
- Collected self-report scores, observational data, heart rate variability, and salivary cortisol levels from 54 children (5-12 years) undergoing diagnostic MRI.
- Analyzed data to assess levels of discomfort and identify associated factors.
Main Results:
- Over half of the children experienced minimal discomfort during MRI.
- No significant association was found between younger age and higher discomfort levels.
- Parental trait anxiety correlated with observational discomfort scores.
- Use of contrast agents requiring venous cannulation was linked to elevated salivary cortisol levels.
Conclusions:
- Pediatric MRI-related discomfort is generally minimal for children aged 5-12.
- Parental anxiety and procedural factors like contrast administration are more influential on discomfort than age alone.
- Findings support the ethical assessment of minimal risk for pediatric research MRI.
Abstract:
Magnetic resonance imaging (MRI) scans for research purposes usually do not directly benefit the children scanned, so that review boards need to assess whether the risk of harm or discomfort is minimal. This study aimed at providing empirical data on discomfort related to unsedated MRI in children aged 5-12 years. Secondary objectives were to determine whether lower age is associated with higher levels of discomfort and to investigate which other characteristics of subjects and/or procedures may be associated with higher levels of discomfort. Self-report scores, observation scores, heart rate standard deviation scores, and incremental salivary cortisol levels were obtained from 54 children aged 5-12 years with non-acute conditions undergoing diagnostic MRI. Of the 54 children, 10 scored relatively high values on the self-report score and on one or two of the other measures, and another 15 scored relatively high on the self-report score alone. Rather than an age effect, associations were found between parents' trait anxiety and observation score values and between use of contrast fluid (requiring the insertion of a venous cannula) and high incremental salivary cortisol levels. In conclusion, MRI-related discomfort may be regarded as minimal for more than half of children aged 5-12.
Related Concept Videos
Imaging Studies I: CT and MRI
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Imaging Studies for Cardiovascular System IV: CMRI
Magnetic Resonance Imaging
Imaging Studies IV: Magnetic Resonance Imaging
Radiological Investigation I: X-ray and CT
Imaging Studies III: Computed Tomography
