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Oligonucleotide microarrays with high discriminating power for the detection of single nucleotide variations in the

Bee Hak Hong1, Soon Jin Oh, Jimin Ju

  • 1Division of Molecular and Life Sciences and POSTECH Biotech Center, Pohang University of Science and Technology, Pohang 790-784, Korea.

Molecules and Cells
|December 2, 2010
PubMed
Abstract

No abstract available in PubMed .

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DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...