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Updated: Jun 6, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
The increased risk of community-acquired methicillin-resistant Staphylococcus aureus neck abscesses in young children
Praveen Duggal1, Iman Naseri, Steven E Sobol
1Department of Otolaryngology-Head and Neck Surgery, Emory University School of Medicine, Atlanta, Georgia, USA.
Insights
Pediatric deep neck infections are often caused by Staphylococcus aureus (SA), particularly methicillin-resistant SA (MRSA) in younger children and those with lateral neck abscesses. This highlights a need for targeted treatment strategies.
Area of Science:
- Pediatric Infectious Diseases
- Microbiology
- Otolaryngology
Background:
- Deep neck space infections (DNSIs) in children necessitate surgical intervention.
- Understanding the microbiological etiology of pediatric DNSIs is crucial for effective treatment.
Purpose of the Study:
- To investigate the microbiological origins of pediatric deep neck space infections requiring surgery.
- To identify risk factors associated with specific pathogens in pediatric DNSIs.
Main Methods:
- Retrospective cohort study of 136 pediatric patients surgically treated for deep neck space abscesses.
- Analysis of demographic, clinical, and microbiological data from September 2004 to August 2009.
- Comparison of bacterial isolates, including methicillin-resistant Staphylococcus aureus (MRSA) and non-S. aureus (N-SA) pathogens.
Main Results:
- Staphylococcus aureus (SA) was a common pathogen, with methicillin-resistant SA (MRSA) comprising 58% of SA isolates.
- Patients younger than 16 months were 10 times more likely to have SA infections.
- Lateral neck abscesses and African American ethnicity were associated with increased risk of SA and MRSA infections.
Conclusions:
- Younger children (<16 months) and those with lateral neck abscesses face a higher risk of SA infections, predominantly MRSA.
- Early identification of these risk factors is essential for guiding management of pediatric deep neck space infections.
Objectives/Hypothesis:
To analyze the microbiological origins of deep neck space infections requiring surgical intervention in a pediatric population.
Study Design:
Retrospective cohort study.
Methods:
The study population (N = 136) included all pediatric patients surgically treated for deep neck space abscesses in a metropolitan tertiary care children's hospital over the course of 5 years (September 2004-August 2009). Demographic and clinical information was compared with microbiological isolate data.
Results:
Microbiological analysis of 118 bacterial isolates demonstrated 49 (42%) methicillin-resistant Staphylococcus aureus (MRSA), 35 (30%) methicillin-sensitive S. aureus, and 34 (28%) non-S. aureus (N-SA) isolates. The median age was 16 months (range, 1 month-13years). Patients <16 months of age were 10 times more likely to have an S. aureus (SA) infection versus N-SA (P <.0001). MRSA comprised the majority of all SA isolates (58%). Eighty percent of all SA abscesses were located in the lateral neck. African American pediatric patients accounted for 70% of all deep neck space infections, and 86% of all MRSA infections. Clindamycin resistance was noted in 8% (4/49) of all community-acquired MRSA isolates.
Conclusions:
Children younger than 16 months and/or with lateral neck abscesses are at a significantly increased risk of having an SA infection, the majority being MRSA.
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