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Comparison of the remineralizing potential of child formula dentifrices
Manikandan Ekambaram1, Anut Itthagarun, Nigel Martyn King
1Paediatric Dentistry, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR.
Background:
Although child formula fluoridated dentifrices can be used safely by young children their remineralizing capability remains questionable.
Aims:
To evaluate the remineralizing potential of child formula dentifrices on primary teeth.
Design:
In vitro single-section technique utilizing a 7 days pH-cycling model.
Methods:
Primary teeth were placed in demineralizing solution for 96 h to produce artificial carious lesions 100 μm deep, and then cut longitudinally into 50 sections 100-150 μm thick and randomly assigned to five groups. Sections in Groups A to D were treated with dentifrices containing 500 ppm AmF, 500 ppm MFP, 500 ppm MFP and xylitol, or 500 ppm NaF, respectively. Group E sections were treated with a nonfluoridated dentifrice.
Outcome Measurements:
Lesions were evaluated using polarized light microscopy and microradiography.
Results:
Group D (500 ppm NaF) sections exhibited a significant decrease in lesion depth, whereas those in Group E (nonF) showed a significant increase in depth (P<0.05, paired t-test). Decrease in lesion progression was observed in Groups A, B and C.
Conclusions:
The 500 ppm NaF dentifrice demonstrated remineralization of carious lesions by virtue of a significant decrease in lesion depth; whereas dentifrices that contained AmF, MFP and MFP with xylitol decelerated the progression of demineralization.
