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[A clinical study of asymptomatic bacteriospermia]
1Department of Obstetrics and Gynecology, School of Medicine, Yamagata University.
The Japanese Journal of Antibiotics
|January 1, 1990
Summary
Asymptomatic bacteriospermia is common, with Staphylococcus epidermidis and Peptostreptococcus prevalent. Flomoxef (FMOX) demonstrated superior antibacterial activity against isolated semen bacteria compared to other tested antibiotics.
Area of Science:
- Microbiology
- Urology
- Andrology
Context:
- Asymptomatic bacteriospermia affects individuals requiring semen analysis.
- High prevalence of bacterial detection in semen samples.
- Identification of specific aerobic and anaerobic bacterial strains.
Purpose:
- To investigate asymptomatic bacteriospermia as a clinical entity.
- To evaluate the efficacy of various antibiotics in treating bacteriospermia.
- To assess bacterial changes in semen following antibiotic treatment.
Summary:
- Bacterial detection in semen reached 89.2%, with high rates for aerobic (55.4%) and anaerobic (70.8%) bacteria.
- Predominant aerobic strains included Staphylococcus epidermidis and Enterococcus faecalis; Peptostreptococcus dominated anaerobic isolates.
- Flomoxef (FMOX) exhibited superior in vitro antibacterial activity against isolated semen bacteria compared to cefaclor (CCL), cephalexin, lomefloxacin, and latamoxef.
- Oral cefaclor (CCL) treatment in 11 subjects resulted in bacterial clearance but also led to superinfections.
Impact:
- Highlights the significance of asymptomatic bacteriospermia in semen analysis.
- Provides comparative antibiotic efficacy data for treating male reproductive tract infections.
- Suggests potential for superinfections with certain antibiotic treatments, necessitating careful monitoring.