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Related Concept Videos

What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
Cancer-Critical Genes I: Proto-oncogenes01:33

Cancer-Critical Genes I: Proto-oncogenes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
Cancer-Critical Genes I: Proto-oncogenes01:33

Cancer-Critical Genes I: Proto-oncogenes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
Cancers Originate from Somatic Mutations in a Single Cell02:21

Cancers Originate from Somatic Mutations in a Single Cell

Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...
Cancers Originate from Somatic Mutations in a Single Cell02:21

Cancers Originate from Somatic Mutations in a Single Cell

Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...

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[Hippocrates' viewpoint on cancer].

Qi Zheng1, Ke-jun Nan, Huai-lin Zheng

  • 1Oncology Department, Xi'an Jiaotong University, Xi'an, 710061, China.

Zhonghua Yi Shi Za Zhi (Beijing, China : 1980)
|December 3, 2010
PubMed
Summary
This summary is machine-generated.

Hippocrates, the father of medicine, pioneered cancer knowledge by integrating ancient Egyptian medicine with his observations. He established foundational cancer concepts, including its vascularity and palliative care principles still relevant today.

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Area of Science:

  • * Medical History
  • * Oncology
  • * Ancient Medicine

Background:

  • * Inherited ancient Egyptian medical knowledge.
  • * Combined inherited knowledge with personal medical practice and clinical observations.
  • * Established the foundation for understanding cancer in ancient Greece.

Observation:

  • * Defined cancer as a distinct disease category.
  • * Characterized cancerous tumors as highly vascularized with infiltration capabilities.
  • * Investigated cancer pathogenesis through the lens of the ancient Greek
  • Four Humors
  • theory.

Findings:

  • * Advocated for individualized, comprehensive cancer treatment strategies.
  • * Proposed palliative therapy for incurable cancer patients, aligning with modern medical principles.
  • * Emphasized the importance of cancer prognosis and transparent communication with patients' families.

Implications:

  • * Hippocrates' principles of cancer care and patient communication remain influential.
  • * His work laid the groundwork for the development of oncology.
  • * Established ethical considerations in cancer treatment and prognosis.