Relationship between mental states in depression: the assimilation model perspective
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Updated: Jun 6, 2026

Animal Models of Depression - Chronic Despair Model (CDM)
Published on: September 23, 2021
Katerine Osatuke1, William B Stiles, Michael Barkham
1Veterans Health Administration National Center for Organization Development, Ste 230, 11500 Northlake Drive, Cincinnati, OH 45249, USA. Katerine.Osatuke@va.gov
Abstract:
Metacognitive theories describe relationships between mental-affective self-states, including the capacity of one self-state to reflect upon another self-state. The assimilation model is a metacognitive approach that understands self-states as made of traces of experiences at different levels of integration. Psychological problems are understood as impaired accessibility of certain self-states to the person's normal awareness. These states are distressing or otherwise subjectively problematic when they emerge. This exploratory study used the assimilation framework to describe mental states in 17 clients who participated in a clinical trial of cognitive-behavioral therapy for depression. Three clinically sophisticated raters examined transcripts of 1h-long psychotherapy session per client to construct qualitative descriptions of self-states and their relationship patterns in these depressed individuals. We then systematically compared and integrated these raters' descriptions of the clients' self-states. In each case, we found a conflict between two internally incompatible states: an interpersonally submissive state and an interpersonally dominant one, a pattern consistent with the model's theoretical description of depression.
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