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Related Experiment Videos

Intracranial aneurysms: evaluation by MR angiography.

J S Ross1, T J Masaryk, M T Modic

  • 1Department of Radiology, Western Reserve University, Cleveland, OH 44106.

AJNR. American Journal of Neuroradiology
|May 1, 1990
PubMed
Summary

Magnetic Resonance Angiography (MRA) shows promise for detecting intracranial aneurysms. This noninvasive technique accurately visualizes the circle of Willis, aiding in early diagnosis of these vascular abnormalities.

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Area of Science:

  • Neuroradiology
  • Medical Imaging
  • Vascular Neurology

Background:

  • Intracranial aneurysms pose significant health risks.
  • Accurate and noninvasive diagnostic methods are crucial for early detection.
  • Conventional angiography, while effective, is invasive.

Purpose of the Study:

  • To compare the diagnostic accuracy of MR angiography (MRA) with intraarterial digital subtraction angiography (IA DSA) for intracranial aneurysms.
  • To evaluate the effectiveness of MRA in visualizing the circle of Willis.
  • To assess MRA's potential as a screening tool for at-risk patients.

Main Methods:

  • Volume gradient-echo MR angiography (MRA) was performed on 47 patients.
  • MRA findings were compared with IA DSA in 19 patients with confirmed aneurysms.

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  • Sensitivity and specificity were calculated for different MRA evaluation methods.

    • Main Results:

    • MRA demonstrated increasing sensitivity with additional analysis techniques, reaching 86% with cine MRA plus partitions and spin-echo studies.
    • For patients with aneurysms, sensitivity ranged from 73% (cine MRA only) to 95% (cine MRA + partitions + spin-echo).
    • MRA successfully identified aneurysms as small as 3-4 mm in the circle of Willis.

    Conclusions:

    • MRA is a valuable tool for detecting intracranial aneurysms.
    • The technique offers high sensitivity and specificity, especially with advanced analysis.
    • MRA shows significant potential as a noninvasive screening examination for intracranial vasculature.