Related Experiment Videos

Lyme disease of the CNS: MR imaging findings in 14 cases

R E Fernandez1, M Rothberg, G Ferencz

  • 1Department of Radiology, Community Medical Center, Toms River, NJ 08755.

Insights

Magnetic resonance imaging (MRI) revealed abnormalities in 43% of patients diagnosed with Lyme disease and central nervous system (CNS) complaints. Abnormal signals were found in the brainstem and cerebral white matter.

Area of Science:

  • Neurology
  • Radiology
  • Infectious Diseases

Background:

  • Lyme disease can present with neurological complications affecting the central nervous system (CNS).
  • Diagnostic challenges exist in identifying CNS involvement in Lyme disease.

Purpose of the Study:

  • To evaluate the utility of Magnetic Resonance (MR) imaging in diagnosing Lyme disease with CNS complaints.
  • To identify characteristic MR imaging findings in patients with confirmed Lyme disease and neurological symptoms.

Main Methods:

  • Retrospective review of MR imaging scans from 14 patients.
  • Patients had clinical diagnoses of Lyme disease, CNS complaints, and positive Lyme titers.
  • Analysis of MR imaging for signal abnormalities in the brain.

Main Results:

  • 43% of reviewed MR examinations showed abnormalities.
  • Abnormal signal areas were identified in the cerebral white matter.
  • Abnormal signal areas were also observed in the brainstem.

Conclusions:

  • MR imaging can detect abnormalities in patients with Lyme disease and CNS involvement.
  • Cerebral white matter and brainstem are potential sites for MR imaging findings in neuroborreliosis.
  • MR imaging may aid in the diagnosis and assessment of neurological Lyme disease.

Related Concept Videos