A note on case-control sampling to estimate kappa coefficients
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Updated: Sep 24, 2026

qKAT: Quantitative Semi-automated Typing of Killer-cell Immunoglobulin-like Receptor Genes
Published on: March 6, 2019
1Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, California 94305.
Abstract:
The feasibility and cost-effectiveness of estimation of kappa using a case-control method of sampling, proposed by Jannarone, Macera, and Garrison (1987, Biometrics 43, 433-437), is provided support. However, in this article unrealistic assumptions in their presentation are identified and more general results for more realistic settings are provided.
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