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Related Concept Videos

Hypodermis01:02

Hypodermis

The hypodermis (the subcutaneous layer or superficial fascia) is present directly below the dermis. It connects the skin to the underlying fascia (fibrous tissue) of the bones and muscles. It is not strictly a part of the skin, although the border between the hypodermis and dermis can be difficult to distinguish. The hypodermis consists of well-vascularized, loose, areolar connective tissue and adipose tissue, which functions as a mode of fat storage and provides insulation and cushioning for...
Fats as Energy Storage Molecules01:06

Fats as Energy Storage Molecules

Triglycerides are a form of long-term energy storage molecules. They are made of glycerol and three fatty acids. To obtain energy from fat, triglycerides must first be broken down by hydrolysis into their two principal components, fatty acids and glycerol. This process, called lipolysis, takes place in the cytoplasm. The resulting fatty acids are oxidized by β-oxidation into acetyl-CoA, which is used by the Krebs cycle. The glycerol that is released from triglycerides after lipolysis directly...
Overview of Lipid Metabolism01:24

Overview of Lipid Metabolism

Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...
Loose Connective Tissue01:26

Loose Connective Tissue

Loose connective tissue is found between many organs. Its main function is to absorb shock and bind tissues together. It also allows water, salts, and various nutrients to diffuse into cells that are embedded in it or present in adjacent tissues.
Adipose Tissue
Adipose tissue consists primarily of fat storage cells called adipocytes and little extracellular matrix. A large number of capillaries present within adipose tissue allow rapid mobilization of lipid molecules. White adipose tissue is...

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Related Experiment Video

Updated: Jun 6, 2026

Identification and Dissection of Diverse Mouse Adipose Depots
06:31

Identification and Dissection of Diverse Mouse Adipose Depots

Published on: July 11, 2019

Basic science review on adipose tissue for clinicians.

Spencer A Brown1, Benjamin Levi, Charlotte Lequex

  • 1Dallas, Texas; and Stanford, Calif. From the Department of Plastic Surgery, University of Texas Southwestern Medical Center, and the Department of Surgery, Division of Plastic Surgery, Stanford University School of Medicine.

Plastic and Reconstructive Surgery
|December 3, 2010
PubMed
Summary
This summary is machine-generated.

Fat contains stem cells, driving research into adipose-derived stem cell applications. Despite increased clinical use, the U.S. Food and Drug Administration has not yet approved these stem cell treatments for medical indications.

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Related Experiment Videos

Last Updated: Jun 6, 2026

Identification and Dissection of Diverse Mouse Adipose Depots
06:31

Identification and Dissection of Diverse Mouse Adipose Depots

Published on: July 11, 2019

Exploring Adipose Tissue Structure by Methylsalicylate Clearing and 3D Imaging
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Published on: August 19, 2020

Human Subcutaneous Adipose Tissue Sampling Using a Mini-Liposuction Technique
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Human Subcutaneous Adipose Tissue Sampling Using a Mini-Liposuction Technique

Published on: September 27, 2021

Area of Science:

  • Regenerative Medicine
  • Biotechnology

Background:

  • Fat tissue is recognized as a source of stem cells.
  • Adipose-derived stem cells (ASCs) have garnered significant research interest.
  • Recent advancements illuminate ASCs' potential in various clinical settings.

Purpose of the Study:

  • To explore the expanding clinical applications of fat and ASCs.
  • To review novel research in tissue engineering and stem cell transformation.
  • To address the growing concerns regarding the safety and efficacy of ASC-based therapies.

Main Methods:

  • Review of current literature on fat harvesting and ASC isolation.
  • Analysis of ASC differentiation properties and potential.
  • Examination of clinical use trends and regulatory status.

Main Results:

  • Significant increase in the global and U.S. utilization of fat grafts and ASCs.
  • Emerging research into novel tissue-engineered constructs using ASCs.
  • Transformation of ASCs into induced pluripotent stem cells is under investigation.

Conclusions:

  • Adipose-derived stem cells show promise but require further safety and efficacy validation.
  • The clinical application of isolated ASCs is increasing rapidly.
  • Regulatory approval from bodies like the U.S. Food and Drug Administration is pending for medical indications.