Hybrid procedures for the treatment of aortic arch aneurysms

Aortic arch aneurysms present a significant clinical challenge. Historically, open repair has been the mainstay of therapy, but it is associated with significant morbidity and mortality. In particular, the risk of stroke is not insignificant. The development of endovascular therapies has allowed for the less invasive treatment of thoracic aortic aneurysms using endograft therapy. This treatment is limited by the need for "healthy" aorta proximal and distal to the aneurysm in order to get an appropriate seal. This limits use of endografts in the aortic arch as treatment of aneurysms in this location would necessitate coverage of critical brachiocephalic vessels including the innominate and left carotid arteries. To overcome these limitations, hybrid approaches to arch aneurysm repair have been developed. These include partial arch reconstruction through a median sternotomy, or extra-anatomic arch vessel bypass depending on the location of the aneurysm and the patients overall medical condition. These are accompanied by the placement of a thoracic stent-graft at the same setting (either antegrade or retrograde) or at a subsequent procedure. Outcomes evaluating these procedures are just beginning to become available in significant numbers. The outcomes, however, demonstrate these are durable procedures that may provide a viable alternative to conventional aortic arch surgery. As experience with these procedures grows, our understanding of the factors affecting outcomes will be clearer, and the use of these procedures will become associated with even lower morbidities and mortality. The further evolution of aortic endograft technology, however, will ultimately allow for complete endovascular treatment of the entire aortic arch.