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Updated: Jun 6, 2026
A Method for 3D Reconstruction and Virtual Reality Analysis of Glial and Neuronal Cells
Published on: September 28, 2019
JULIDE: a software tool for 3D reconstruction and statistical analysis of autoradiographic mouse brain sections
Delphine Ribes1, Julia Parafita, Rémi Charrier
1Signal Processing Laboratory (LTS5), Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Abstract:
In this article we introduce JULIDE, a software toolkit developed to perform the 3D reconstruction, intensity normalization, volume standardization by 3D image registration and voxel-wise statistical analysis of autoradiographs of mouse brain sections. This software tool has been developed in the open-source ITK software framework and is freely available under a GPL license. The article presents the complete image processing chain from raw data acquisition to 3D statistical group analysis. Results of the group comparison in the context of a study on spatial learning are shown as an illustration of the data that can be obtained with this tool.
