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Increased activity of circulating polymorphonuclear leukocytes in acute myocardial infarction
M Radomski1, K Herbaczyńska-Cedro, L Ceremuzyński
1Medical Research Centre, Polish Academy of Sciences, Warsaw.
International Journal of Cardiology
|June 1, 1990
Abstract:
Acute myocardial infarction results in an increased sensitivity of circulating polymorphonuclear leukocytes to ex vivo aggregation. This increase was prevented by pretreatment of leukocytes with BW755, but not with aspirin, suggesting that the activation of blood leukocytes in infarction is due to a stimulation of cellular lipoxygenase.