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Disorders of the Male Reproductive System01:20

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Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
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Updated: Jun 6, 2026

Nerve-sparing Mid-urethral Obstruction (NeMO) in Female Small Rodents
07:42

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Published on: April 25, 2017

Overactive bladder and outlet obstruction in men.

Doreen E Chung1, Jaspreet S Sandhu

  • 1Mount Sinai Hospital, University of Chicago, IL 60608, USA.

Current Urology Reports
|December 3, 2010
PubMed
Summary
This summary is machine-generated.

Antimuscarinic drugs effectively treat overactive bladder (OAB) and lower urinary tract symptoms (LUTS) in men, even those with benign prostatic hyperplasia (BPH). Combination therapies offer safe and effective options for managing these common conditions.

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Last Updated: Jun 6, 2026

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Area of Science:

  • Urology
  • Pharmacology

Background:

  • Lower urinary tract symptoms (LUTS), overactive bladder (OAB), and benign prostatic hyperplasia (BPH) are prevalent in men.
  • Antimuscarinics are a primary pharmacotherapy for OAB.

Purpose of the Study:

  • To evaluate the efficacy and safety of antimuscarinic agents in men with LUTS and BPH.
  • To explore combination therapies for managing BPH and OAB.

Main Methods:

  • Review of clinical trials investigating antimuscarinic use in men with LUTS.
  • Analysis of treatment outcomes for monotherapy and combination therapies.

Main Results:

  • Antimuscarinics demonstrate efficacy and safety in treating men with LUTS, with or without BPH.
  • Combination therapy with α-blockers, 5-α-reductase inhibitors, or surgery shows effectiveness.

Conclusions:

  • Antimuscarinics are a viable treatment option for men with LUTS and OAB, including those with BPH.
  • Combination strategies enhance treatment outcomes for benign prostatic hyperplasia and overactive bladder.