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In-vitro synergy testing of nine antimicrobial combinations against Listeria monocytogenes
A P MacGowan1, H A Holt, D S Reeves
1Department of Microbiology, Southmead Hospital, Westbury-on-Trym, Bristol, UK.
The Journal of Antimicrobial Chemotherapy
|April 1, 1990
Abstract:
In-vitro antimicrobial synergy against Listeria monocytogenes was assessed using nine combinations in chequerboard (bacteriostatic) tests and time-kill (bactericidal) studies. Ampicillin/gentamicin and trimethoprim/sulphamethoxazole were the most synergistic combinations in bacteristatic tests, whereas gentamicin with ampicillin, trimethoprim or vancomycin and trimethoprim/sulphamethoxazole were the most synergistic in bactericidal tests. Gentamicin-containing combinations were most effective at killing L. monocytogenes and those containing rifampicin least effective.