Costs related to medical treatment for common cardiovascular risk factors

P Turek1, J Lietava, V Foltan

  • 1Pharmaceutical Faculty, Comenius University, Bratislava, Slovakia.

Insights

Indirect costs associated with cardiovascular diseases like hypertension, metabolic syndrome, and diabetes mellitus significantly outweigh direct pharmacotherapeutic expenses. Diabetes mellitus incurs the highest indirect financial burden, emphasizing the need for comprehensive cost-management strategies.

Area of Science:

  • Cardiovascular disease research
  • Health economics
  • Public health policy

Background:

  • Cardiovascular diseases (CVDs) pose a significant global health challenge.
  • Hypertension (HT), metabolic syndrome (MS), and diabetes mellitus (DM) are prevalent CVDs with substantial economic impact.
  • Understanding the direct and indirect costs of these conditions is crucial for resource allocation and healthcare planning.

Purpose of the Study:

  • To evaluate the direct and indirect economic costs associated with hypertension (HT), metabolic syndrome (MS), and diabetes mellitus (DM) in the Slovak Republic.
  • To compare the pharmacotherapeutic costs across these conditions and their combinations.
  • To assess the relative financial burden of direct versus indirect costs.

Main Methods:

  • Analysis of data from 1,000 patients randomly selected from the NEMESYS database (total 10,300 patients).
  • Calculation of average annual direct pharmacotherapeutic costs for HT, MS, DM, and their combinations, stratified by gender.
  • Estimation of indirect costs, particularly focusing on patients with diabetes mellitus.

Main Results:

  • Direct pharmacotherapeutic costs varied by condition and gender, with higher costs for diabetes mellitus (approx. 392 Euros/year for men, 384 Euros/year for women).
  • Combined diagnoses (HT+MS+DM) resulted in the highest direct costs (approx. 452 Euros/year for men, 455 Euros/year for women).
  • Indirect costs represented a substantially greater financial burden, with diabetes mellitus patients incurring the highest indirect costs (approx. 5,227 Euros/year for men, 5,365 Euros/year for women).

Conclusions:

  • Direct pharmacotherapeutic costs increase with disease severity.
  • Gender-based cost differences were less pronounced in more severe conditions.
  • Indirect costs were 13 to 17 times higher than direct pharmacotherapeutic costs, highlighting their significant economic impact.
Abstract

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