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Potential clinical applications of C-reactive protein
J M Okamura1, J M Miyagi, K Terada
1John A. Burns School of Medicine, University of Hawaii, Manoa, Honolulu 96822.
Journal of Clinical Laboratory Analysis
|January 1, 1990
Summary
C-reactive protein (CRP) is a sensitive marker for inflammation and tissue injury. This review covers its clinical uses in diagnosis, monitoring disease, and screening.
Area of Science:
- Biochemistry
- Clinical Medicine
- Immunology
Background:
- C-reactive protein (CRP) is an acute-phase protein.
- CRP serves as a sensitive biomarker for inflammation and tissue injury.
- Its detection involves a simple, rapid, and cost-effective latex agglutination assay.
Purpose of the Study:
- To review the clinical applications of C-reactive protein (CRP).
- To highlight CRP's role in diagnostic support.
- To discuss serial CRP measurements for evaluating disease progression and treatment efficacy.
Main Methods:
- Literature review of clinical applications of CRP.
- Analysis of diagnostic support capabilities.
- Evaluation of serial CRP measurements in disease monitoring.
- Review of screening studies utilizing CRP.
Main Results:
- CRP is a valuable tool for diagnosing inflammatory conditions and tissue damage.
- Serial CRP measurements effectively track disease activity and response to therapy.
- CRP screening studies demonstrate its utility in various clinical settings.
Conclusions:
- C-reactive protein (CRP) is a versatile and clinically significant biomarker.
- Its ease of use and sensitivity make it invaluable for patient management.
- Further applications in screening and diagnostics are supported by current evidence.