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Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
08:05

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane

Published on: December 9, 2022

Clinical and angiographic outcomes after percutaneous recanalization of chronic total saphenous vein graft occlusion

Rasha Al-Lamee1, Alfonso Ielasi, Azeem Latib

  • 1San Raffaele Scientific Institute, Milan, Italy.

The American Journal of Cardiology
|December 4, 2010
PubMed

Insights

Percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) in saphenous vein grafts (SVGs) using modern techniques showed favorable outcomes despite high restenosis rates. Repeat revascularization was often needed but graft patency was achievable.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Vascular Surgery

Background:

  • Long-term outcomes after percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) in saphenous vein grafts (SVGs) are often poor.
  • Limited data exist on modern PCI techniques for SVG CTO.

Purpose of the Study:

  • To assess the efficacy and long-term outcomes of PCI in SVG CTO.
  • To evaluate the routine use of embolic protection devices and drug-eluting stents in this patient group.

Main Methods:

  • Retrospective cohort analysis of 34 patients with SVG CTO undergoing PCI between May 2002 and July 2009.
  • Successful SVG recanalization with stent implantation was achieved in 68% of patients.
  • Embolic protection devices were used in 78%, and 95% of implanted stents were drug-eluting.

Main Results:

  • No in-hospital major adverse cardiac events in the successful PCI group.
  • One myocardial infarction occurred in the unsuccessful group during hospitalization.
  • At a median follow-up of 18 months, one myocardial infarction occurred in the successful group.
  • In-stent restenosis rate was 68%, with 61% requiring target vessel revascularization.

Conclusions:

  • Successful PCI for SVG CTO using modern techniques yields favorable clinical outcomes.
  • High repeat revascularization rates were observed, but graft patency can be restored with reintervention.

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