Related Experiment Video

Updated: Jun 6, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
07:24

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

[Fungal endogenous endophthalmitis]

B Bodaghi1

  • 1Service d'ophtalmologie, hôpital Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, 75013 Paris, France. bahram.bodaghi@psl.aphp.fr

Journal Francais D'Ophtalmologie
|December 4, 2010
PubMed

Insights

Endogenous endophthalmitis, a rare eye infection from systemic sources, requires prompt diagnosis and treatment. Early intervention with antimicrobials and surgery improves visual outcomes in this challenging condition.

Area of Science:

  • Ophthalmology
  • Infectious Diseases

Context:

  • Endogenous endophthalmitis is a rare but severe intraocular infection.
  • It originates from a distant systemic infection, often bacterial or fungal.
  • Accounts for 5-10% of all endophthalmitis cases.

Purpose:

  • To review the etiology, diagnosis, and management of endogenous endophthalmitis.
  • To highlight the importance of early recognition and treatment for visual preservation.

Summary:

  • Ocular involvement stems from systemic abscesses with varying virulence.
  • Clinical presentation can mimic panuveitis, delaying diagnosis.
  • Ancillary tests identify the infectious source and causative agent.
  • Treatment involves systemic/intravitreal antimicrobials and potentially pars plana vitrectomy.
  • Visual prognosis remains guarded despite aggressive therapy.

Impact:

  • Prompt diagnosis and targeted antimicrobial therapy are crucial.
  • Education for ophthalmologists and infectious disease specialists can reduce diagnostic delays.
  • Effective management aims to prevent permanent vision loss.

More Related Videos

Establishing Fungal Entomopathogens as Endophytes: Towards Endophytic Biological Control15:14

Establishing Fungal Entomopathogens as Endophytes: Towards Endophytic Biological Control

Published on: April 11, 2013

Related Concept Videos

Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
Microbiome of the Eye01:22

Microbiome of the Eye

The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
Candidiasis01:20

Candidiasis

Candidiasis is a fungal infection caused by opportunistic species of Candida. It can affect various anatomical sites, including the skin, oral cavity, nails, and genitourinary tract. Among its forms, vaginal candidiasis is the most common type of mucosal infection. It typically results from the overgrowth of Candida albicans in the vaginal mucosa. Under normal conditions, C. albicans exists as a commensal organism within the vaginal microbiota, regulated by the dominance of lactobacilli, which...