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Updated: Jun 6, 2026
07:24
Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
[Fungal endogenous endophthalmitis]
1Service d'ophtalmologie, hôpital Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, 75013 Paris, France. bahram.bodaghi@psl.aphp.fr
Journal Francais D'Ophtalmologie
|December 4, 2010
Summary
Endogenous endophthalmitis, a rare eye infection from systemic sources, requires prompt diagnosis and treatment. Early intervention with antimicrobials and surgery improves visual outcomes in this challenging condition.
Area of Science:
- Ophthalmology
- Infectious Diseases
Context:
- Endogenous endophthalmitis is a rare but severe intraocular infection.
- It originates from a distant systemic infection, often bacterial or fungal.
- Accounts for 5-10% of all endophthalmitis cases.
Purpose:
- To review the etiology, diagnosis, and management of endogenous endophthalmitis.
- To highlight the importance of early recognition and treatment for visual preservation.
Summary:
- Ocular involvement stems from systemic abscesses with varying virulence.
- Clinical presentation can mimic panuveitis, delaying diagnosis.
- Ancillary tests identify the infectious source and causative agent.
- Treatment involves systemic/intravitreal antimicrobials and potentially pars plana vitrectomy.
- Visual prognosis remains guarded despite aggressive therapy.
Impact:
- Prompt diagnosis and targeted antimicrobial therapy are crucial.
- Education for ophthalmologists and infectious disease specialists can reduce diagnostic delays.
- Effective management aims to prevent permanent vision loss.
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