Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Opioid Analgesics: Synthetic and Semisynthetic Opioids01:15

Opioid Analgesics: Synthetic and Semisynthetic Opioids

Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
Opioid Analgesics: Morphine and Other Natural Cogeners01:20

Opioid Analgesics: Morphine and Other Natural Cogeners

Opioids are a class of drugs that mimic endogenous opioid peptides and act on opioid receptors, and help in pain relief. These compounds are classified as natural, synthetic, or semi-synthetic. Natural opioids, like morphine, codeine, and thebaine, are derived from the opium poppy plant (Papaver somniferum or Papaver album) and are termed opiates. Synthetic opioids are artificial, while semi-synthetic opioids combine natural and synthetic compounds. Morphine, a prototypical opioid, possesses a...
Pharmaceutical Poisoning: Potential Scenarios01:26

Pharmaceutical Poisoning: Potential Scenarios

Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
Opioid Receptors: Overview01:22

Opioid Receptors: Overview

Opioid receptors, including the mu (μ, MOR), delta (δ, DOR), and kappa (κ, KOR) types, belong to the rhodopsin family of G protein-coupled receptors. These receptors are located throughout the central and peripheral nervous systems and in non-neuronal tissues such as macrophages and astrocytes. Opioid receptor ligands can be categorized into agonists or antagonists. Highly selective agonists include [d-Ala2, MePhe4, Gly(ol)5]-enkephalin or DAMGO for MOR, [D-Pen2, D-Pen5]-enkephalin or DPDPE for...
Prescription, Nonprescription and Orphan Drugs01:02

Prescription, Nonprescription and Orphan Drugs

Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
Drug Abuse and Addiction: Pharmacological Phenomena01:15

Drug Abuse and Addiction: Pharmacological Phenomena

Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not necessarily...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Near-Infrared Responsive Property and Nanozyme Effect-Mediated 3D-Printed Gradient Bioactive Scaffold for Intelligent Immunomodulation in Regeneration of Large Segmental Bone Defects.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

IL-6-induced endothelial microparticles exacerbate juvenile ischemic osteonecrosis by promoting Osteoclastogenesis: Implications for Perthes disease.

Cellular signalling·2026
Same author

Analyzing the association between ferritin levels and ICP using machine learning algorithms: a retrospective case-control study.

Frontiers in medicine·2026
Same author

Active chitosan hydrogel loaded with polydopamine-coated regeneration silicon for advanced treatment of root caries.

International journal of biological macromolecules·2026
Same author

Single-cell RNA sequencing analysis reveals the evolution and regulatory features of specialized endothelial cell subsets in non-traumatic osteonecrosis of the femoral head.

Biology direct·2026
Same author

Mechanisms linking parents' education level to adolescent gaming disorder among Chinese Special School students: serial mediating effects of emotional abuse experience and psychopathy.

BMC psychology·2026

Related Experiment Video

Updated: Jun 6, 2026

Fentanyl Analog Screening using LC-TIMS-TOF MS/MS
10:13

Fentanyl Analog Screening using LC-TIMS-TOF MS/MS

Published on: November 8, 2024

Chinese narcotics trafficking: a preliminary report.

Kaicheng Huang1, Jianhong Liu, Ruohui Zhao

  • 1Center for Drugs, Crime, and Public Policy, Southwest University of Political Science and Law, Chongqing, P.R. China. skyhkch@yahoo.com.cn

International Journal of Offender Therapy and Comparative Criminology
|December 4, 2010
PubMed
Summary
This summary is machine-generated.

This study quantitatively examines drug trafficking via the "China Route." Findings suggest this route is active, but traditional organized crime syndicates are not the primary offenders.

More Related Videos

Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones
06:06

Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones

Published on: February 5, 2018

Related Experiment Videos

Last Updated: Jun 6, 2026

Fentanyl Analog Screening using LC-TIMS-TOF MS/MS
10:13

Fentanyl Analog Screening using LC-TIMS-TOF MS/MS

Published on: November 8, 2024

Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones
06:06

Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones

Published on: February 5, 2018

Area of Science:

  • Criminology
  • Law
  • Sociology

Background:

  • The existence and nature of the "China Route" for drug smuggling and trafficking remain debated.
  • Existing research relies heavily on qualitative data, lacking comprehensive quantitative analysis.
  • Understanding offender profiles, especially the role of traditional organized crime, is crucial.

Purpose of the Study:

  • To quantitatively assess the significance of the "China Route" in drug trafficking.
  • To analyze the characteristics of offenders involved in drug offenses via this route.
  • To determine the extent to which traditional organized criminal syndicates are involved.

Main Methods:

  • Systematic data collection from court sentencing files.
  • Analysis of data from seven high courts covering the "China Route".
  • Application of logistic regression to identify associations between offender characteristics and offense types.

Main Results:

  • Evidence consistent with the operation of the "China Route" was found.
  • No substantial evidence supports the involvement of traditional organized criminal syndicates in the majority of offenses.
  • Logistic regression identified significant associations between offender attributes and offense categories.

Conclusions:

  • The "China Route" appears to be a relevant pathway for drug trafficking.
  • Offenders are likely not primarily members of traditional organized crime groups.
  • Further research into offender characteristics and motivations is warranted.