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Published on: August 14, 2018
Metal-Assisted and Microwave-Accelerated Evaporative Crystallization
Melissa A Pinard1, Kadir Aslan
1Morgan State University, Department of Chemistry, Baltimore, Maryland 21251, United States.
Abstract:
We describe a platform technology, called metal-assisted and microwave-assisted evaporative crystallization (MA-MAEC), based on the combined use of silver nanoparticles and microwave heating for selective and rapid crystallization of small molecules. In this regard, the crystallization of a model small molecule (glycine) was achieved in several seconds. Glycine crystals grown on silver nanostructures with and without microwave heating were found to be larger than those grown on blank glass slides. The MA-MAEC technique has the potential to selectively grow the desired polymorphs of small molecules "on-demand" in a fraction of the time as compared to the conventional evaporative crystallization.
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