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Related Experiment Videos

Intracranial aneurysms: evaluation by MR angiography.

J S Ross1, T J Masaryk, M T Modic

  • 1Department of Radiology, University Hospitals of Cleveland/Case Western Reserve University, OH 44106.

AJR. American Journal of Roentgenology
|July 1, 1990
PubMed
Summary

Magnetic Resonance Angiography (MRA) shows promise for detecting intracranial aneurysms, offering a noninvasive screening tool for at-risk patients. This technique can identify aneurysms as small as 3-4 mm in the circle of Willis.

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Area of Science:

  • Neuroradiology
  • Medical Imaging

Background:

  • Intracranial aneurysms pose a significant risk.
  • Accurate and noninvasive diagnostic methods are crucial for early detection.

Purpose of the Study:

  • To compare the diagnostic accuracy of MR angiography (MRA) with intraarterial digital subtraction angiography (IA DSA) for identifying intracranial aneurysms.
  • To evaluate the effectiveness of different MRA techniques in aneurysm detection.

Main Methods:

  • 47 patients underwent MRA using a velocity-compensated gradient-echo sequence.
  • Findings were compared with IA DSA in 19 patients with confirmed aneurysms.
  • Sensitivity and specificity were calculated for various MRA evaluation methods.

Main Results:

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  • MRA sensitivity ranged from 67% (cine MRA only) to 86% (cine MRA + partitions + spin-echo studies) for detecting aneurysms.
  • In patients with aneurysms, sensitivity varied from 73% to 95% with advanced MRA techniques.
  • MRA successfully visualized the circle of Willis, detecting aneurysms as small as 3-4 mm.

Conclusions:

  • MRA is a promising noninvasive screening tool for intracranial aneurysms.
  • Advanced MRA techniques significantly improve sensitivity and specificity in aneurysm detection.
  • MRA can effectively define the circle of Willis for aneurysm screening.