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Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
Published on: March 3, 2023
Coping with antibiotic resistance: the impending crisis
1Department of Medical Microbiology, Aberdeen Royal Infirmary, Foresterhill, UK. i.m.gould@abdn.ac.uk
International Journal of Antimicrobial Agents
|December 7, 2010
Summary
Antibiotic resistance is increasing due to global changes and climate shifts. Antibiotic stewardship is crucial for preserving drug effectiveness amid a drug development crisis.
Area of Science:
- Microbiology
- Environmental Science
- Pharmacology
Background:
- Global antibiotic production and usage patterns are shifting.
- Climate change may exacerbate the spread of antibiotic resistance.
- There is a significant crisis in the development of new antibiotic drugs.
Purpose of the Study:
- To highlight the growing threat of antibiotic resistance.
- To emphasize the critical role of antibiotic stewardship.
- To underscore the need for preserving existing antibiotic efficacy.
Main Methods:
- This study is a review and synthesis of current trends.
- Analysis of global antibiotic production and usage data.
- Assessment of climate change impacts on microbial resistance.
Main Results:
- Antibiotic resistance is projected to increase globally.
- Synergistic effects between climate change and antibiotic use accelerate resistance.
- The pipeline for new antibiotics is critically limited.
Conclusions:
- Antibiotic stewardship is essential for conserving the effectiveness of current antibiotics.
- Urgent strategies are needed to combat rising antibiotic resistance.
- Preserving the activity of existing antibiotics is paramount due to development challenges.
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