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Related Concept Videos

Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
mTOR Signaling and Cancer Progression03:03

mTOR Signaling and Cancer Progression

The mammalian target of rapamycin or mTOR protein was discovered in 1994 due to its direct interaction with rapamycin. The protein gets its name from a yeast homolog called TOR. The mTOR protein complex in mammalian cells plays a major role in balancing anabolic processes such as the synthesis of proteins, lipids, and nucleotides and catabolic processes, such as autophagy in response to environmental cues, such as availability of nutrients and growth factors.
The mTOR pathway or the...
Cancer-Critical Genes I: Proto-oncogenes01:33

Cancer-Critical Genes I: Proto-oncogenes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
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Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
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Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Cancer-Critical Genes II: Tumor Suppressor Genes01:05

Cancer-Critical Genes II: Tumor Suppressor Genes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
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Related Experiment Video

Updated: Jun 6, 2026

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
07:25

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

Published on: March 6, 2018

[Prostate cancer].

S Vieillot1, P Fenoglietto, N Aillères

  • 1Département de cancérologie radiothérapie, Université Montpellier I, CRLC Val d'Aurelle, Montpellier, France. sabinevieillot@yahoo.fr

Cancer Radiotherapie : Journal De La Societe Francaise De Radiotherapie Oncologique
|December 7, 2010
PubMed
Summary
This summary is machine-generated.

Three-dimensional conformal radiotherapy is an effective treatment for localized prostate cancer, improving dose distribution and sparing nearby organs. This technique requires detailed knowledge of prostate radio-anatomy and disease characteristics.

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Area of Science:

  • Oncology
  • Radiation Oncology

Background:

  • Localized prostate cancer treatment has evolved significantly.
  • Radiation therapy is a widely accepted and efficacious modality.
  • Advancements enable precise dose delivery, preserving organs at risk.

Observation:

  • Three-dimensional conformal radiotherapy (3D-CRT) offers improved dose adaptation.
  • This technique allows for increased total radiation dose to the target volume.
  • Accurate radio-anatomy and disease knowledge are crucial for effective treatment planning.

Findings:

  • 3D-CRT enhances the adaptation of radiation dose distribution.
  • Preservation of organs at risk is a key benefit of conformal techniques.
  • The study details prostate cancer epidemiology and radio-anatomy.

Implications:

  • Conformal radiation modalities represent a significant advancement in prostate cancer care.
  • This approach necessitates a comprehensive understanding of prostate radio-anatomy and disease progression.
  • A case report illustrates the application of conformal radiation techniques.